Antihistamine intermediate

1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzimidazole Hydrochloride

Advanced bilastine intermediate carrying the N-ethoxyethyl benzimidazole-piperidine fragment.

CAS No.: 1841081-72-0
Molecular formula: C₁₆H₂₃N₃O · HCl
Mol. weight: 309.84 g/mol
Appearance: White to off-white crystalline solid
API target: Bilastine (CAS 202189-78-4)

Description

Coupled with 4-(2-chloroethyl)-α,α-dimethyl phenyl acetic acid in the final N-alkylation step to deliver bilastine. The HCl salt simplifies isolation and improves storage stability.

Applications

Bilastine final N-alkylation

Other products

4-Chloro Benzophenone

C₁₃H₉ClO

4-Chloro Benzhydrol

C₁₃H₁₁ClO

4-Chloro Benzhydryl Piperazine

C₁₇H₁₉ClN₂

(R)-(4-Chlorophenyl)(phenyl)methanamine

C₁₃H₁₂ClN