Antidepressant intermediate

3-(4-Chlorobutyl)-1H-indole-5-carbonitrile

Chlorobutyl-indole carbonitrile — the alkyl-indole fragment in the vilazodone SSRI/5-HT1A partial agonist.

CAS No.: 143612-79-7
Molecular formula: C₁₃H₁₃ClN₂
Mol. weight: 232.71 g/mol
Appearance: Off-white crystalline solid
API target: Vilazodone hydrochloride (CAS 163521-12-8)

Description

A key advanced intermediate in vilazodone manufacture. The terminal chloride is displaced by the 5-(piperazinyl)benzofuran fragment to assemble the full vilazodone scaffold in a single N-alkylation step.

Applications

Vilazodone hydrochloride synthesis

Other products

4-Chloro Benzophenone

C₁₃H₉ClO

4-Chloro Benzhydrol

C₁₃H₁₁ClO

4-Chloro Benzhydryl Piperazine

C₁₇H₁₉ClN₂

(R)-(4-Chlorophenyl)(phenyl)methanamine

C₁₃H₁₂ClN