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5-Bromo Indole structure

Antimigraine intermediate

5-Bromo Indole

Halogenated indole used as the cross-coupling and alkylation handle in the eletriptan scaffold.

CAS No.
10075-50-0
Molecular formula
C₈H₆BrN
Mol. weight
196.05 g/mol
Appearance
Off-white to pale brown crystalline solid
API target
Eletriptan hydrobromide (CAS 143322-58-1)

Description

5-Bromo indole is the indole building block that delivers the bromoaryl handle for Suzuki and Heck couplings in eletriptan and other tryptamine-derived APIs.

Applications

  • Eletriptan hydrobromide synthesis
  • Tryptamine and indole chemistry